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Taking antioxidants daily helps reduce inflammations of any kind. Antioxidants strengthen our capillaries, arteries, veins, and blood vessel walls; they also improve circulation, joint flexibility, skin smoothness, and elasticity. When choosing between the antioxidants Pycnogenol and Grape Seed Extract, let me tell you that both have an excellent research record and will have many similar, positive effects in the body. Only three differences give Grape Seed Extract the edge.